This teacher has left his mark on every student he has ever taught.

这老师对他所教过的每个学生都留下深刻的影响。

leave one's mark (on)留下某人的永久影响力或印象，如果表明对谁人造成影响要用介词on.
The scary experience left its mark on every victim.这可怕的经历让每个受难者都留下难以磨灭的印象。